enflog® is an innovative blend of proteolytic enzymes: it contains Bromain, extracted from the pineapple stem, Papain, derived from papaya, and Fungal Protease extracted from the Aspergillus Oryzae fungus.
Proteolytic enzymes
Proteolytic enzymes are enzymes capable of breaking protein bonds. Some of these enzymes act on proteins that are released during inflammatory processes.
Bromelain, extracted from the pineapple stem, is useful in controlling the evolution of inflammatory processes. Its maximum activity is achieved when the pH* is between 5.5 and 8.
Papain, extracted from the immature papaya fruit, has an action similar to that of Bromelain. It performs its activity best at pH* levels between 4 and 7.
Fungal Protease is obtained from the fermentation of the Aspergillus Oryzae fungus. It carries out its activity over a wide pH* range (between 3 and 9).
*pH is the measure of a substance’s acidity. Its value ranges between 0 and 14. If the pH is equal to 7, the substance is neutral, while pH values lower than 7 indicate acidity and pH values higher than 7 indicate alkalinity.
Once ingested, proteolytic enzymes are at risk of being rapidly degraded in the stomach, failing to reach the intestinal walls where they should be absorbed.
For this reason, it is important to develop appropriate strategies to protect the enzymes from the acidic environment of the stomach:
- gastro-protected capsules: encapsulating proteolytic enzymes in coatings capable of resisting gastric juices ensures their absorption in the intestine.
- liposomal form, which allows for the administration of proteolytic enzymes even in non-encapsulated powder form.
