{"version":"1.0","provider_name":"Future Live Srl","provider_url":"https:\/\/www.future-live.com\/en\/","title":"enflog\u00ae in urogenital infections - Future Live Srl","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"GY5bLqRFYa\"><a href=\"https:\/\/www.future-live.com\/en\/enflog-patent\/enflog-in-urogenital-infections\/\">enflog\u00ae in urogenital infections<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/www.future-live.com\/en\/enflog-patent\/enflog-in-urogenital-infections\/embed\/#?secret=GY5bLqRFYa\" width=\"600\" height=\"338\" title=\"&#8220;enflog\u00ae in urogenital infections&#8221; &#8212; Future Live Srl\" data-secret=\"GY5bLqRFYa\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script type=\"text\/javascript\">\n\/* <![CDATA[ *\/\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/* ]]> *\/\n<\/script>\n","description":"[vc_row][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;15057&#8243; img_size=&#8221;full&#8221; onclick=&#8221;custom_link&#8221; link=&#8221;https:\/\/www.future-live.com\/en\/enflog-patent\/&#8221;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_single_image image=&#8221;14975&#8243; img_size=&#8221;medium&#8221; alignment=&#8221;center&#8221;][vc_separator css=&#8221;.vc_custom_1771105941519{padding-top: 20px !important;padding-bottom: 10px !important;}&#8221;][vc_column_text]enflog\u00ae is a mixture of proteolytic enzymes developed to act in synergy and with high specificity toward protein substrates of biological interest. Recently, it has proven capable of counteracting the defense mechanisms implemented by certain bacteria, particularly biofilm formation. Its use serves as an innovative support in contexts where the biofilm represents an obstacle to the effectiveness of conventional therapies for the treatment of bacterial infections. Thanks to its patented formulation, enflog\u00ae can act in a targeted manner on the protein substrates that make up the biofilm matrix, making bacteria more vulnerable and easier to counteract.[\/vc_column_text][tm_spacer size=&#8221;lg:30&#8243;][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/6&#8243;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][tm_spacer size=&#8221;lg:30&#8243;][vc_column_text] The role of biofilm in urogenital infections [\/vc_column_text][vc_column_text] Urogenital tract infections represent a issue of major clinical relevance, primarily due to their frequency and their tendency to recur over time. Among the microorganisms most frequently involved, Escherichia coli (E. coli) stands out\u2014a bacterium normally present in the intestine that can reach the urinary tract and cause infections, including recurrent cystitis and other forms of urinary tract infection. One of the aspects that makes counteracting these infections particularly complex is the ability of certain bacteria, including E. coli, to organize themselves into protective structures called biofilms. A biofilm is an organized biological matrix composed of different components, including proteins and other extracellular substances, within which bacteria can adhere to biological surfaces and find protection from adverse environmental conditions and the action of antimicrobial agents. In the urogenital context, these mechanisms can contribute to bacterial persistence and the difficulty of eradicating certain infections, favoring conditions associated with recurrence.[\/vc_column_text][tm_spacer size=&#8221;lg:60&#8243;][\/vc_column][vc_column width=&#8221;1\/6&#8243;][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/6&#8243;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][tm_spacer size=&#8221;lg:30&#8243;][vc_column_text] enflog\u00ae: the enzymatic approach to bacterial biofilm [\/vc_column_text][vc_column_text] In questo contesto si inserisce la ricerca su enflog\u00ae, una miscela brevettata di enzimi proteolitici composta da bromelina, papaina e proteasi da Aspergillus oryzae. The formulation was developed to act synergistically on protein substrates of biological interest. Studies conducted have investigated the ability of enflog\u00ae to interfere with bacterial defense mechanisms, with a focus on biofilm formation and structure. Interest in its application within the urogynaecological field stems precisely from the possibility of targeting the protein component of the biofilm matrix, aiming to leave bacteria more exposed and vulnerable to the action of conventional treatments. [\/vc_column_text][tm_spacer size=&#8221;lg:60&#8243;][\/vc_column][vc_column width=&#8221;1\/6&#8243;][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/6&#8243;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text] Scientific evidence on the efficacy of enflog\u00ae [\/vc_column_text][tm_spacer size=&#8221;lg:10&#8243;][vc_column_text]The efficacy of the enflog\u00ae enzymatic mixture is supported by scientific studies evaluating its action on bacterial biofilm, highlighting results of high statistical significance (****). In particular, a study demonstrated that enflog\u00ae is capable of: reducing Escherichia coli biofilm formation by 82.81% (p&lt;"}