{"id":15597,"date":"2024-04-05T20:38:37","date_gmt":"2024-04-05T18:38:37","guid":{"rendered":"https:\/\/www.future-live.com\/ingredients\/d-mannose\/"},"modified":"2026-04-28T14:01:04","modified_gmt":"2026-04-28T12:01:04","slug":"d-mannose","status":"publish","type":"page","link":"https:\/\/www.future-live.com\/en\/ingredients\/d-mannose\/","title":{"rendered":"D-Mannose"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column width=&#8221;1\/6&#8243;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text]<span style=\"color: #000000;\"><strong>D-Mannose<\/strong> is a monosaccharide capable of preventing the adhesion of harmful bacteria to the bladder walls, <strong>reducing the risk of<\/strong> <span style=\"color: #005595;\"><a style=\"color: #005595;\" href=\"https:\/\/www.future-live.com\/en\/recurrent-cystitis\/\"><strong>recurrent cystitis<\/strong><\/a>.<\/span><br \/><\/span>[\/vc_column_text][tm_spacer size=&#8221;lg:60&#8243;][vc_custom_heading text=&#8221;What is D-Mannose?<br \/>&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23005595&#8243; use_theme_fonts=&#8221;yes&#8221;][tm_spacer size=&#8221;lg:30&#8243;][vc_column_text]<span style=\"color: #000000;\"><strong>D-Mannose<\/strong> is a simple sugar found in small quantities in some fruits and in birch and larch wood.<\/span><\/p>\n<p><span style=\"color: #000000;\">Unlike glucose, which has a similar structure, D-Mannose is only partially metabolized. For this reason,<strong> it does not provide a significant amount of calories<\/strong>, therefore it does not cause weight gain and does not raise blood sugar levels.<br \/> <\/span>[\/vc_column_text][tm_spacer size=&#8221;lg:60&#8243;][vc_custom_heading text=&#8221;How does it work?<br \/>&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23005595&#8243; use_theme_fonts=&#8221;yes&#8221;][tm_spacer size=&#8221;lg:30&#8243;][vc_column_text]<span style=\"color: #000000;\">When <a style=\"color: #000000;\" href=\"https:\/\/www.future-live.com\/en\/cystitis\/\"><strong>cystitis<\/strong><\/a> occurs, harmful bacteria such as <em>Escherichia coli <\/em>attach themselves to the bladder walls, causing inflammation and pain.<\/span><\/p>\n<p><span style=\"color: #000000;\"><strong>D-Mannose acts as an anti-adhesive agent, helping to prevent harmful bacteria from attaching to the bladder walls<\/strong>. In fact, it possesses a high affinity for the fimbriae\u2014the anchoring organs\u2014of many bacteria, particularly<em> E. coli<\/em>, to which it binds, competitively inhibiting their adhesion to the bladder mucosa. <\/span><\/p>\n<p><span style=\"color: #000000;\">D-Mannose is excreted through the urine, carrying the bacteria away with it, thus reducing the risk of infection and recurrence.<br \/><\/span>[\/vc_column_text][tm_spacer size=&#8221;lg:60&#8243;][vc_single_image image=&#8221;13001&#8243; img_size=&#8221;large&#8221; alignment=&#8221;center&#8221;][tm_spacer size=&#8221;lg:60&#8243;][vc_custom_heading text=&#8221;D-Mannose: a clinical study<br \/>&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23005595&#8243; use_theme_fonts=&#8221;yes&#8221;][tm_spacer size=&#8221;lg:30&#8243;][vc_column_text]<span style=\"color: #000000;\">A randomized clinical trial\u2014a study in which treatment assignment occurred randomly\u2014demonstrated that<strong> D-Mannose is effective in preventing cystitis recurrences<\/strong>.<\/span><\/p>\n<p><span style=\"color: #000000;\">Following the initial antibiotic treatment of acute phase cystitis, 205 women with a history of recurrent cystitis were divided into two groups.<\/span><\/p>\n<p><span style=\"color: #000000;\">One group received a prophylaxis of 2g of D-Mannose per day for 6 months, while the control group received no prophylaxis.<\/span><\/p>\n<p><span style=\"color: #000000;\">At the end of the study, the group treated with D-Mannose experienced a recurrence rate of 14.6%, compared to the control group where cystitis recurrences occurred in 60.8% of patients.<\/span><\/p>\n<p><span style=\"color: #000000;\">It was therefore demonstrated that a daily dose of 2g of D-Mannose has a significantly superior effect compared to the group without prophylaxis and is effective in preventing recurrences.<\/span>[\/vc_column_text][tm_spacer size=&#8221;lg:60&#8243;][vc_single_image image=&#8221;12995&#8243; img_size=&#8221;large&#8221; alignment=&#8221;center&#8221;][tm_spacer size=&#8221;lg:60&#8243;][vc_column_text]<span style=\"color: #000000;\"><em>*The data reported in the table were extrapolated from the clinical study by <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s00345-013-1091-6\">Kranj\u010dec et al. (2014)<\/a><\/em><\/span><\/p>\n<p><span style=\"color: #000000;\"><em>For more information on the clinical study, click here:<br \/>\n<span id=\"sample-permalink\"><a href=\"https:\/\/www.future-live.com\/d-mannosio-studio-clinico-2014\/\">https:\/\/www.future-live.com\/<span id=\"editable-post-name\">d-mannosio-studio-clinico-2014<\/span>\/<\/a> \u200e<\/span><\/em><\/span>[\/vc_column_text][tm_spacer size=&#8221;lg:60&#8243;][vc_custom_heading text=&#8221;D-Mannose: side effects<br \/>&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23005595&#8243; use_theme_fonts=&#8221;yes&#8221;][tm_spacer size=&#8221;lg:30&#8243;][vc_column_text]<span style=\"color: #000000;\"><strong>The intake of D-Mannose does not present significant side effects.<\/strong> At high doses, it can cause mild intestinal disturbances, which generally disappear within a few days.<\/span>[\/vc_column_text][tm_spacer size=&#8221;lg:60&#8243;][\/vc_column][vc_column width=&#8221;1\/6&#8243;][\/vc_column][\/vc_row][vc_row][vc_column][vc_separator][tm_spacer size=&#8221;lg:60&#8243;][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;16068&#8243; img_size=&#8221;full&#8221; alignment=&#8221;right&#8221; onclick=&#8221;custom_link&#8221; link=&#8221;https:\/\/www.future-live.com\/en\/products\/enzuryl-d-mannosio-14-sachets\/&#8221;][\/vc_column][vc_column width=&#8221;1\/2&#8243;][vc_column_text]<\/p>\n<h3 style=\"text-align: center;\"><strong><span style=\"color: #005595;\">EnzUryl D-Mannose <\/span><\/strong><\/h3>\n<h3 style=\"text-align: center;\"><strong><span style=\"color: #005595;\">14 sachets<\/span><\/strong><\/h3>\n<p>[\/vc_column_text][tm_spacer size=&#8221;lg:30&#8243;][vc_btn title=&#8221;Learn more&#8221; style=&#8221;custom&#8221; custom_background=&#8221;#005599&#8243; custom_text=&#8221;#ffffff&#8221; shape=&#8221;round&#8221; size=&#8221;lg&#8221; align=&#8221;center&#8221; link=&#8221;url:https%3A%2F%2Fwww.future-live.com%2Fen%2Fproducts%2Fenzuryl-d-mannosio-14-sachets%2F|title:EnzUryl%C2%AE%20D-Mannosio%2014%20bustine|&#8221;][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"[vc_row][vc_column width=&#8221;1\/6&#8243;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text]D-Mannose is a monosaccharide capable of preventing the adhesion of harmful bacteria to the bladder walls, reducing the risk of recurrent cystitis.[\/vc_column_text][tm_spacer size=&#8221;lg:60&#8243;][vc_custom_heading text=&#8221;What is D-Mannose?&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23005595&#8243; use_theme_fonts=&#8221;yes&#8221;][tm_spacer size=&#8221;lg:30&#8243;][vc_column_text]D-Mannose is a simple sugar found in small quantities in some fruits and in birch and larch wood. Unlike glucose, which has a similar structure, D-Mannose is only partially metabolized. For this reason, it does not provide a significant amount of calories, therefore it does not cause weight gain and does not raise blood sugar levels. [\/vc_column_text][tm_spacer size=&#8221;lg:60&#8243;][vc_custom_heading text=&#8221;How does it work?&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23005595&#8243; use_theme_fonts=&#8221;yes&#8221;][tm_spacer size=&#8221;lg:30&#8243;][vc_column_text]When cystitis occurs, harmful bacteria such as Escherichia coli attach themselves to the bladder walls, causing inflammation and pain. D-Mannose acts as an anti-adhesive agent, helping to prevent harmful bacteria from attaching to the bladder walls. In fact, it possesses a high affinity for the fimbriae\u2014the anchoring organs\u2014of many bacteria, particularly E. coli, to which it binds, competitively inhibiting their adhesion to the bladder mucosa. D-Mannose is excreted through the urine, carrying the bacteria away with it, thus reducing the risk of infection and recurrence.[\/vc_column_text][tm_spacer size=&#8221;lg:60&#8243;][vc_single_image image=&#8221;13001&#8243; img_size=&#8221;large&#8221; alignment=&#8221;center&#8221;][tm_spacer size=&#8221;lg:60&#8243;][vc_custom_heading text=&#8221;D-Mannose: a clinical study&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23005595&#8243; use_theme_fonts=&#8221;yes&#8221;][tm_spacer size=&#8221;lg:30&#8243;][vc_column_text]A randomized clinical trial\u2014a study in which treatment assignment occurred randomly\u2014demonstrated that D-Mannose is effective in preventing cystitis recurrences. Following the initial antibiotic treatment of acute phase cystitis, 205 women with a history of recurrent cystitis were divided into two groups. One group received a prophylaxis of 2g of D-Mannose per day for 6 months, while the control group received no prophylaxis. At the end of the study, the group treated with D-Mannose experienced a recurrence rate of 14.6%, compared to the control group where cystitis recurrences occurred in 60.8% of patients. It was therefore demonstrated that a daily dose of 2g of D-Mannose has a significantly superior effect compared to the group without prophylaxis and is effective in preventing recurrences.[\/vc_column_text][tm_spacer size=&#8221;lg:60&#8243;][vc_single_image image=&#8221;12995&#8243; img_size=&#8221;large&#8221; alignment=&#8221;center&#8221;][tm_spacer size=&#8221;lg:60&#8243;][vc_column_text]*The data reported in the table were extrapolated from the clinical study by Kranj\u010dec et al. (2014) For more information on the clinical study, click here: https:\/\/www.future-live.com\/d-mannosio-studio-clinico-2014\/ \u200e[\/vc_column_text][tm_spacer size=&#8221;lg:60&#8243;][vc_custom_heading text=&#8221;D-Mannose: side effects&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23005595&#8243; use_theme_fonts=&#8221;yes&#8221;][tm_spacer size=&#8221;lg:30&#8243;][vc_column_text]The intake of D-Mannose does not present significant side effects. At high doses, it can cause mild intestinal disturbances, which generally disappear within a few days.[\/vc_column_text][tm_spacer size=&#8221;lg:60&#8243;][\/vc_column][vc_column width=&#8221;1\/6&#8243;][\/vc_column][\/vc_row][vc_row][vc_column][vc_separator][tm_spacer size=&#8221;lg:60&#8243;][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;16068&#8243; img_size=&#8221;full&#8221; alignment=&#8221;right&#8221; onclick=&#8221;custom_link&#8221; link=&#8221;https:\/\/www.future-live.com\/en\/products\/enzuryl-d-mannosio-14-sachets\/&#8221;][\/vc_column][vc_column width=&#8221;1\/2&#8243;][vc_column_text] EnzUryl D-Mannose 14 sachets [\/vc_column_text][tm_spacer size=&#8221;lg:30&#8243;][vc_btn title=&#8221;Learn more&#8221; style=&#8221;custom&#8221; custom_background=&#8221;#005599&#8243; custom_text=&#8221;#ffffff&#8221; shape=&#8221;round&#8221; size=&#8221;lg&#8221; align=&#8221;center&#8221; link=&#8221;url:https%3A%2F%2Fwww.future-live.com%2Fen%2Fproducts%2Fenzuryl-d-mannosio-14-sachets%2F|title:EnzUryl%C2%AE%20D-Mannosio%2014%20bustine|&#8221;][\/vc_column][\/vc_row]","protected":false},"author":178,"featured_media":0,"parent":14743,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - 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